You can add a new layout as per your need by clicking on Add Layout button (top-right corner) from the listing page. You will be redirected to the Add Layout page where you need to insert the following details:
Layout Title: Enter the Layout title.
Store Views: Select the Store that you want to display the layout in.
Apply This Layout: By ticking this checkbox, this layout will be applied.
After inserting all the details, click on the Save Layout button. As you click on it, the Layout will be displayed in the list of Home Page Layouts.
Already applied Layout will be displayed in Active Layout status. By clicking on Apply as default button, the App’s Home page will be displayed based on that Layout.